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- 传出神经分植物神经和运动神经,前者支配心肌、平滑肌和腺体等,后者支配骨骼肌。植物神经分交感和副交感(副交感节前纤维常在迷走神经内走行),交感兴奋时效应器表现为应急时的状态,副交感兴奋时效应器表现为睡眠时的状态。 ACh、AChE相关药 拟胆碱药分两类,兴奋受体抑制酶 匹罗卡品作用眼,外用治疗青光眼 阿托交替芸香碱,防止虹膜晶状粘 贝胆碱、腹气胀,兴奋泌尿和胃肠 新斯地明抗酯酶,主治重症肌无力 术
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- <a href="/tags/%E8%8D%AF%E7%90%86/">#药理</a>
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- 激动药 药物种类 麻黄碱、多巴胺,α β 肾上腺 去甲肾、间羟胺,β 只有异丙肾 肾上腺素 α β 受体兴奋药,肾上腺素是代表 血管收缩血压升,局麻用它延时间 局部止血效明显,过敏休克当首选 心脏兴奋气管扩,哮喘持续它能缓 心跳骤停用三联,应用注意心血管 α 受体被阻断,升压作用能翻转 心衰高压脑硬化,甲亢糖尿都禁用 多巴胺 α β 多巴胺,心脏兴奋血压升 肾脏调节分两种,中低多巴血流增 高浓α
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- 拟胆碱药物是(A) A Physostigmine B Anisodamine C Solifenacin D Scopolamine E Atropine 主要发挥中枢抗胆碱作用的药物是(A) A 东莨菪碱 B 毒扁豆碱 C 山莨菪碱 D 阿托品 E 毛果芸香碱 去甲肾上腺素治疗消化道出血时的给药途径为(A) A 口服 B 肌内注射 C 舌下给药 D 皮下注射 E 静脉滴注 A
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- 2022-10-07
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- <a href="/tags/%E8%8D%AF%E7%90%86/">#药理</a>
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- 【迁移】导出SingleR需要的数据
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- loom文件使用记录 随着单细胞数据量的增长,计算要求成指数增长,当数据量大于10万个细胞的时候,seurat包分析就显得非常有压力了,因为在实时内存中储存数据就变得非常困难,HDF5数据格式提供了高效的磁盘存储,而不是在内存中存储数据,这就将分析扩展到大规模数据集,甚至可以达到大于100万细胞的级别 ,Linnarson实验室开发了一种基于hdf5的数据结构,loom,可以方便地存储单细胞基因组
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- 买了一台零刻 SER5 Pro 32G作为虚拟机的宿主机,用了一个月感觉还行,准备加装一个铠侠TC10 1T SATA3固态。小心排线接口上有个黑色的东东,先用镊子挑起来再拔。然后虚拟机设置里添加磁盘。 挂载磁盘并设置开机自动mount sudo su fdisk -l #i查看可挂载磁盘 mkfs.ext4 /dev/sdb #格式化为ext4 # apt install util-linux
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- 安装补充包 conda activate seurat conda install -c conda-forge r-nmf -y conda install -c conda-forge r-fastica -y 获取非负表达矩阵 使用《使用metacell进行分群聚类》中的数据 1234567891011121314151617sce <- readRDS('SRX8890
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- 预处理 12345678910111213141516171819202122232425262728293031f_QC_plot <- function(sce){ options(repr.plot.width = 12, repr.plot.height = 6) print(Seurat::VlnPlot(sce, features = c("nFe
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- 处理参考样本 12345678910111213ref_sce <- readRDS('~/upload/zl_liu/data/pca.rds')ref_sce <- subset(ref_sce, group == 'CRPC')table(ref_sce@meta.data$cell_type_fig3)g2m_genes <- Se
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- 安装包 conda create -n seurat -c conda-forge r-seurat=4.1.1 -y conda activate seurat conda install -c conda-forge r-tidyverse -y conda install -c conda-forge r-irkernel -y Rscript -e “IRkernel::installs
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